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BRANCHED CHAIN AMINO ACIDS deliver a scientifically-validated BCAA ratio of Leucine, Valine and Isoleucine. The precise 2:1:1 ratio is exactly what many clinical studies have used to support muscle growth and performance!
ESSENTIAL AMINO ACIDS
BCAAs are a group of essential amino acids that play a key role in protein synthesis (a.k.a. muscle growth) and energy production. BCAAs include L-leucine, L-Valine and L-Isoleucine. BCAAs make up 35 to 40% of essential amino acids in total body protein.
DECREASED PLASMA BCAA LEVELS
BCAAs are essential amino acids and cannot be made by the body. They must be ingested through food or supplementation. During exercise, BCAA metabolism in muscle tissue is increased. Therefore, after aerobic exercise (i.e., cardio) and anaerobic exercise (i.e., weight training) there is a significant decrease in plasma BCAA levels in muscle tissue.
PERFORMANCE, GROWTH & RECOVERY
Supplementation with BCAAs prevents the exercise-induced decline in plasma BCAAs and increases BCAA concentration in muscle tissue. BCAA’s are the only amino acids that are not readily degraded in the liver. Therefore, an increase in supplemental BCAA’s can reliably increase their concentration in blood and muscle tissue! The end results: better performance, growth and recovery support!
Numerous scientific studies suggest the positive effects that BCAAs can have on protein synthesis (muscle growth). BCAAs stimulate protein synthesis through multiple pathways. One of the major mechanisms by which BCAAs stimulate protein synthesis is through leucine’s activity in the mammalian target of rapamycin (mTOR) pathway. Several human studies suggest increased protein synthesis and decreased protein breakdown when BCAA’s are supplemented before, during, and after exercise.
BCAAs can have a glycogen sparing effect and can help maintain muscle and liver glycogen stores during exercise. By sparing glycogen, BCAAs can increase fuel supply to working muscle during exercise, resulting in greater performance!
An additional mechanism for exercise performance support from BCAAs is inhibition of central nervous system (CNS) fatigue. Exercise causes an increase in serotonin levels, and this can cause CNS fatigue. Since BCAA’s share the same transporter system with tryptophan (the serotonin precursor amino acid), BCAA supplementation causes competitive inhibition of tryptophan transport to the brain, which in turn reduces serotonin levels. Exercise increases the tryptophan/BCAA ratio in the bloodstream, and a BCAA supplement may prevent or reverse this. This means that BCAA’s could increase exercise performance by decreasing build up of serotonin in the brain. Multiple studies suggest that BCAA supplements successfully change the BCAA/tryptophan plasma ratio, especially during more prolonged exercise.